The Information Science & Technology Center at Colorado State University
Genomic Analysis    
Professor P. Shing Ho (Chair of the Biochemistry and Molecular Biology deparment) is leading an effort to perform large scale genomic analysis of various phyla to study the evolution of functional DNA sequences. A recent endeavor by Professor Ho is a comparative phylogenomic analysis to study the evolutionary relationships between GC content, CpG-dinuleotide content (CpGs), potential nuclear factor I (NFI) binding sites, and potential Z-DNA forming regions (ZDRs) as representative structural and functional GC-rich genomic elements. Professor Ho's study is highly computationally intensive and has been done on a cluster of Linux machines using eight to 32 nodes of computing power. Sequences and annotations of prokaryotic genomes were accessed from the National Center for Biotechnology Information (NCBI) and eukaryotic genomes from the Ensembl database.

 

 

 

Last updated: 11/07/08
Colorado State University Homepage The Information Science & Technology Center - Homepage High Performance Computing (HPC) at CSU - Homepage